Man City vs RB Leipzig has all to play for as they will square off for a spot in the quarter-finals of the Champions League.
With the first leg in Germany ending 1-1 and the abolition of the away goals rule, it's truly all to play for here. Whichever side wins on the night will secure their place in the next round.
City are looking to add a fifth consecutive win in all competitions and are undoubtedly the form team here, with Leipzig a little all over the place when it comes to recent results.
Phil Foden gave fans a scare by revealing he had hurt his foot, although the England international shook that off to play an hour against Crystal Palace and should be raring to go for this one.
Christopher Nkunku is back on the sidelines after picking up a hamstring injury, going off in this month's loss to Dortmund in which Xaver Schlager suffered what could be a season-ending injury of his own.
Peter Gulacsi and Abdou Diallo remain out.
Manchester City and RB Leipzig are on an even footing as far as the head-to-head record is concerned and have won one game apiece out of the three matches played between the two teams.
After a run of nine consecutive matches against German opponents in the UEFA Champions League, Manchester City have won only one of their last four such games in the competition.
After their victory against Tottenham Hotspur in 2019, RB Leipzig have lost each of their last three away games against English clubs in the UEFA Champions League.
Man City(4-3-3): Ederson; Walker, Akanji, Dias, Ake; Rodri; De Bruyne, Gundogan; Mahrez, Haaland, Grealish
RB Leipzig (4-2-3-1): Blaswich; Henrichs, Orban, Gvardiol, Halstenberg; Laimer, Haidara; Szoboszlai, Forsberg, Werner; Silva
Ederson; Walker, Akanji, Orban, Gvardiol, De Bruyne, Laimer,Szoboszlai, Forsberg, Werner, Haaland, Grealish.