Sunday afternoon's north London derby sees Tottenham Hotspur vs Arsenal square off at Tottenham Hotspur Stadium with the two sides chasing alternate targets in the second half of the season.
Tottenham have spluttered and failed to kick into gear throughout the season but remain close enough to the clubs eyeing up Champions League qualification.
However, the Gunners have produced their finest run of form in years to sit at the top of the Premier League.
The normal derby day bragging rights are at stake in what could prove to be a pivotal matchday in both clubs' seasons.
Spurs boss Antonio Conte gave positive updates on a number of key players during his pre-match press conference.
The Italian revealed he expects Dejan Kulusevski to be available, while Rodrigo Bentancur and Richarlison are progressing from their injuries. Their matchday involvement remains in doubt, however.
Matt Doherty and Ivan Perisic have emerged as the standout wing back candidates in recent weeks and both should start. Lucas Moura remains perennially injured but Yves Bissouma was back in training after dropping out of the Spurs side that beat Portsmouth in the FA Cup.
Gabriel Jesus and Reiss Nelson are Arsenal's only confirmed injury absentees for the short trip across north London.
Bukayo Saka is expected to shake off a knock suffered at Oxford, where Emile Smith Rowe returned from his own respective injury.
Eddie Nketiah will continue to lead the line in Jesus' absence, but otherwise manager Mikel Arteta will likely stick with his regular XI which has sent Arsenal to the top of the Premier League.
Martin Odegaard is in fine form, contributing three goals and three assists in his last four outings, and he was rewarded for a prolonged streak of excellence with the Premier League's Player of the Month award for November and December. Mikel Arteta won the manager's equivalent prize.
Arsenal have a good record against Tottenham Hotspur and have won 85 out of the 206 matches played between the two teams, as opposed to Tottenham Hotspur's 67 victories.
Tottenham Hotspur are unbeaten in their last eight Premier League home games against Arsenal and have won their last three such matches in the competition.
Arsenal could complete a league double against Tottenham Hotspur for the first time since the 2013-14 season – the last time they won an away Premier League game against Spurs.
Tottenham Starting 11 (3-4-3): Lloris; Romero, Dier, Lengley; Doherty, Hojbjerg, Bissouma, Perisic; Kulusevski, Kane, Son.
Arsenal Starting XI (4-3-3): Ramsdale; White, Saliba, Gabriel, Zinchenko; Odegaard, Partey, Xhaka; Saka, Nketiah, Martinelli.
For more Tottenham Hotspur vs Arsenal news, follow Sportz Point.